{
 "as_of": "2026-11-06",
 "cmr": "uk-cm-kg/LSE/CIZ",
 "fence": "The page is the record's research on the issuer — no analyst, no rating, no view.",
 "markdown": "The page is the record's research on the issuer — no analyst, no rating, no view.\n\n# CIZZLE BIOTECHNOLOGY HOLDINGS PLC (LSE Main Market: CIZ) — research page\n\nAs of 2026-11-06 · uk-cm-kg · record version 1\n\n## Identity and listing\n\nThe issuer is CIZZLE BIOTECHNOLOGY HOLDINGS PLC, listed on the LSE Main Market under ticker CIZ, with ISIN GB00BNG2VN02 and LEI 213800G3OS3SA2J1Y358. Its security type is Corporate, its segment is SSQ3, its sector is Pharmaceuticals and Biotechnology [201030], and its jurisdiction is England and Wales (Companies House jurisdiction field). Its listing status is listed, not halted.\n\n## The disclosure read\n\nThe record holds 30 filings across 28 filing days in the window 2025-11-06 to 2026-11-06. The median gap between filing days is 8 days. The latest filing is dated 2026-11-02, is of type early_warning, and falls 4 days before the record date of 2026-11-06. On the LSE Main Market the median cadence gap is 4 days, the median filings count is 29.0 and the median latency is 3 days across 892 issuers. In the sector Pharmaceuticals and Biotechnology [201030] the median cadence gap is 6.0 days, the median filings count is 42 and the median latency is 4.0 days across 51 issuers.\n\n## Auditor\n\nThe auditor of record is PKF Littlejohn LLP, with its location not on the record. Auditor changes are not on the record, as this register has no lifecycle type map yet.\n\n## Events and halts\n\nListing, delisting, name change, domicile change and segment move are not on the record, as this register has no lifecycle type map yet. The halt flag is listed, not halted.\n\n## Orderability\n\nFor the elective professional client category the outcome is signal ACM-200 and is determinable. For the eligible counterparty category the outcome is signal ACM-200 and is determinable. The rule version is acm-68000/uk/product-governance-fca-prod-sourcebook/r1, and the chapter is as of 2026-11-04.\n\n## Coverage\n\nNo research houses were found on the issuer's own investor-relations page as read.\n\n## Open research\n\nOne openly published research note is on the record, by Hardman & Co Life Sciences Research, dated 2021-05-14.\n\n## Licensed\n\nLicensed research: none loaded. A licensed row is served only to an agent whose firm holds that licence (licensor, entitlement). No licensed row is loaded.\n\n## As-of depth\n\nNo issuer years are sealed. The market's vintage is not sealed, and no earliest sealed date is recorded. The live record began 2026-09-11. The years 2021, 2022, 2023, 2024, 2025 and 2026 are sealed in the store but not served as of a date, and the as-of door answers not_sealed.\n\n## Sources\n\n11 source pages are named on this page; every value above carries its own source page and read date in the numbers.\n\n- https://www.londonstockexchange.com/live-markets/market-data-dashboard/price-explorer (identity.exchange)\n- https://api.londonstockexchange.com/api/gw/lse/instruments/alldata/CIZ (identity.isin)\n- https://find-and-update.company-information.service.gov.uk/company/06133765 (identity.jurisdiction)\n- https://mapping.gleif.org/api/v2/isin-lei/latest/download (identity.lei)\n- https://www.londonstockexchange.com/stock/CIZ/cizzle-biotechnology-holdings-plc/company-page (identity.sector)\n- https://mcp.uk-cm-kg.ai/events/LSE/CIZ (the disclosure lines)\n- https://marketsecurities.fca.org.uk/officiallist (the halt flag)\n- https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotechnology-Holdings-PLC-Final-Annual-report-and-financial-statements-31-December-2023-Final-unsigned-29-April-2024.pdf (the auditor)\n- https://mcp.uk-cm-kg.ai/book/aio.json (the orderability chapter)\n- https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotech-Initiation-report-%E2%80%93-14-May-2021.pdf (open research)\n- https://mcp.uk-cm-kg.ai/record/LSE/CIZ (the record)\n",
 "market": "UK",
 "node": "uk-cm-kg",
 "numbers": {
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   "live_record_began": "2026-09-11",
   "node_history_from": null,
   "node_years_sealed": [],
   "note": "6 years are sealed in the UK store; their Replay split is not built, so the as-of door answers not_sealed and the record is the live record as of 2026-11-06",
   "record_version": 1,
   "sealed": false,
   "store_years_sealed_not_served": [
    "2021",
    "2022",
    "2023",
    "2024",
    "2025",
    "2026"
   ]
  },
  "auditor": {
   "auditor": {
    "read_by": "Tavily regex",
    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotechnology-Holdings-PLC-Final-Annual-report-and-financial-statements-31-December-2023-Final-unsigned-29-April-2024.pdf",
    "state": "confirmed",
    "value": "PKF Littlejohn LLP"
   },
   "auditor_firm_id": {
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    "state": "not_on_record"
   },
   "auditor_location": {
    "market": "UK",
    "state": "not_on_record"
   },
   "changes": {
    "market": "UK",
    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
   }
  },
  "cmr": "uk-cm-kg/LSE/CIZ",
  "coverage": {
   "count": 0,
   "houses": [],
   "pages_checked": [
    {
     "page": "https://cizzlebiotechnology.com/research/",
     "result": "read: 0 of 0 named houses found on the page"
    },
    {
     "page": "https://cizzlebiotechnology.com/app/uploads/2022/02/CIZ-China-strategic-collaboation-8-Feb-2022.pdf",
     "result": "not readable by this rail (404)"
    }
   ],
   "read_by": "Perplexity sonar (search) · page read by this rail",
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   "state": "none_found"
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     "issuers": 892,
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     "median_filings": 29,
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     "name": "LSE Main Market"
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    "sector": {
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     "median_filings": 42,
     "median_latency_days": 4,
     "name": "Pharmaceuticals and Biotechnology [201030]"
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    "ch_resolution": 1,
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    {
     "category": null,
     "date": "2026-11-02",
     "source": "https://www.investegate.co.uk/announcement/rns/cizzle-biotechnology-holdings--ciz/holding-s-in-company/9853459",
     "title": "Holding(s) in Company",
     "type": "early_warning"
    },
    {
     "category": null,
     "date": "2026-10-26",
     "source": "https://www.investegate.co.uk/announcement/rns/cizzle-biotechnology-holdings--ciz/-500-000-subscription-conversion-of-loan-notes/9839977",
     "title": "£500,000 Subscription, conversion of loan notes",
     "type": "regulatory_announcement"
    },
    {
     "category": null,
     "date": "2026-10-23",
     "source": "https://www.investegate.co.uk/announcement/rns/cizzle-biotechnology-holdings--ciz/cizzle-presents-at-synlab-innovation-symposium/9837648",
     "title": "Cizzle presents at SYNLAB Innovation Symposium",
     "type": "regulatory_announcement"
    },
    {
     "category": null,
     "date": "2026-10-15",
     "source": "https://www.investegate.co.uk/announcement/rns/cizzle-biotechnology-holdings--ciz/update-on-launch-of-lung-cancer-test-in-usa/9823592",
     "title": "Update on Launch of Lung Cancer Test in USA",
     "type": "regulatory_announcement"
    },
    {
     "category": null,
     "date": "2026-10-13",
     "source": "https://find-and-update.company-information.service.gov.uk/company/06133765/filing-history/MzU1MDYzMzAxOGFkaXF6a2N4/document?format=pdf&download=0",
     "title": "capital allotment shares — 2026-05-11",
     "type": "ch_capital"
    }
   ],
   "latest_filing_date": "2026-11-02",
   "read": "the node's event lines (list_events_since), as get_filings serves them",
   "source": "https://mcp.uk-cm-kg.ai/events/LSE/CIZ",
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    "source": "https://www.londonstockexchange.com/live-markets/market-data-dashboard/price-explorer (price-explorer feed api.londonstockexchange.com/api/v1/components/refresh, markets=MAINMARKET, categories=EQUITY, showonlylse=true)",
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    "value": "LSE Main Market"
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    "read_date_basis": "the record version as_of",
    "source": "https://api.londonstockexchange.com/api/gw/lse/instruments/alldata/CIZ",
    "state": "confirmed",
    "value": "GB00BNG2VN02"
   },
   "jurisdiction": {
    "read_by": "Companies House REST API (company profile) (jurisdiction field)",
    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://find-and-update.company-information.service.gov.uk/company/06133765",
    "state": "confirmed",
    "value": "England and Wales (Companies House jurisdiction field)"
   },
   "lei": {
    "read_by": "GLEIF ISIN-to-LEI mapping file (daily), LEI by exact ISIN",
    "read_date": "2026-11-09",
    "read_date_basis": "the field",
    "source": "https://mapping.gleif.org/api/v2/isin-lei/latest/download (ISIN GB00BNG2VN02)",
    "state": "sourced",
    "value": "213800G3OS3SA2J1Y358"
   },
   "name": {
    "read_by": "LSE price explorer (exchange list)",
    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://www.londonstockexchange.com/live-markets/market-data-dashboard/price-explorer (price-explorer feed api.londonstockexchange.com/api/v1/components/refresh, markets=MAINMARKET, categories=EQUITY, showonlylse=true)",
    "state": "sourced",
    "value": "CIZZLE BIOTECHNOLOGY HOLDINGS PLC"
   },
   "sector": {
    "read_by": "LSE issuer profile (exchange site)",
    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://www.londonstockexchange.com/stock/CIZ/cizzle-biotechnology-holdings-plc/company-page",
    "state": "sourced",
    "value": "Pharmaceuticals and Biotechnology [201030]"
   },
   "security_type": {
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    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://www.londonstockexchange.com/live-markets/market-data-dashboard/price-explorer (price-explorer feed api.londonstockexchange.com/api/v1/components/refresh, markets=MAINMARKET, categories=EQUITY, showonlylse=true)",
    "state": "sourced",
    "value": "Corporate"
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    "state": "sourced",
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    "state": "sourced",
    "value": "CIZ"
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   "website": {
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    "read_date": "2026-11-06",
    "read_date_basis": "the record version as_of",
    "source": "https://www.londonstockexchange.com/stock/CIZ/cizzle-biotechnology-holdings-plc/company-page",
    "state": "sourced",
    "value": "http://www.cizzlebiotechnology.co.uk"
   }
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    "entitlement",
    "title",
    "date",
    "source"
   ],
   "rows": [],
   "rule": "A licensed row is served only to an agent whose firm holds that licence (licensor, entitlement). No licensed row is loaded."
  },
  "lifecycle": {
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    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
   },
   "domicile_change": {
    "market": "UK",
    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
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   "listing": {
    "market": "UK",
    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
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   "name_change": {
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    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
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   "segment_move": {
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    "reason": "no lifecycle type map for this register yet (SHELF-01: us and ca first)",
    "state": "not_on_record"
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  "market": "UK",
  "node": "uk-cm-kg",
  "numbers_hash": "sha256:11fdd28ca36aa34ef237c9d0f91bd0f200f6f99cb7dcc0bf84eacd569b616f11",
  "open_research": {
   "read_date": "2026-11-12",
   "rows": [
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     "kind": "issuer-sponsored",
     "publisher": "Hardman & Co Life Sciences Research",
     "read_by": "the note's link answers (200 application/pdf); a document, not read as text",
     "read_date": "2026-11-12",
     "source": "https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotech-Initiation-report-%E2%80%93-14-May-2021.pdf",
     "state": "sourced",
     "title": "Cizzle Biotechnology/BOULD — Initiation following re-admission"
    }
   ],
   "state": "found"
  },
  "orderability": {
   "chapter_as_of": "2026-11-04",
   "client_categories": [
    "elective professional client",
    "eligible counterparty"
   ],
   "outcomes": {
    "elective professional client": {
     "determinable": true,
     "signal": "ACM-200"
    },
    "eligible counterparty": {
     "determinable": true,
     "signal": "ACM-200"
    }
   },
   "read": {
    "basis": "one live read per instrument class, halt state and client category on this market; this issuer's group",
    "chapter": "https://mcp.uk-cm-kg.ai/book/aio.json",
    "door": "https://mcp.uk-cm-kg.ai/mcp",
    "tool": "get_orderability"
   },
   "rule_version": "acm-68000/uk/product-governance-fca-prod-sourcebook/r1",
   "section": "uk.aio.v16"
  },
  "record": {
   "as_of": "2026-11-06",
   "url": "https://mcp.uk-cm-kg.ai/record/LSE/CIZ",
   "version": 1
  },
  "schema": "research-numbers v0.1 (USR-01, 2026-11-11)",
  "status": {
   "read_date": "2026-11-09",
   "source": "https://marketsecurities.fca.org.uk/officiallist",
   "value": "listed, not halted"
  }
 },
 "numbers_hash": "sha256:11fdd28ca36aa34ef237c9d0f91bd0f200f6f99cb7dcc0bf84eacd569b616f11",
 "path": "/uk/LSE/CIZ",
 "schema": "research-page v0.1 (USR-02, 2026-11-11)",
 "sections": [
  {
   "id": "identity",
   "text": "The issuer is CIZZLE BIOTECHNOLOGY HOLDINGS PLC, listed on the LSE Main Market under ticker CIZ, with ISIN GB00BNG2VN02 and LEI 213800G3OS3SA2J1Y358. Its security type is Corporate, its segment is SSQ3, its sector is Pharmaceuticals and Biotechnology [201030], and its jurisdiction is England and Wales (Companies House jurisdiction field). Its listing status is listed, not halted.",
   "title": "Identity and listing"
  },
  {
   "id": "disclosure",
   "text": "The record holds 30 filings across 28 filing days in the window 2025-11-06 to 2026-11-06. The median gap between filing days is 8 days. The latest filing is dated 2026-11-02, is of type early_warning, and falls 4 days before the record date of 2026-11-06. On the LSE Main Market the median cadence gap is 4 days, the median filings count is 29.0 and the median latency is 3 days across 892 issuers. In the sector Pharmaceuticals and Biotechnology [201030] the median cadence gap is 6.0 days, the median filings count is 42 and the median latency is 4.0 days across 51 issuers.",
   "title": "The disclosure read"
  },
  {
   "id": "auditor",
   "text": "The auditor of record is PKF Littlejohn LLP, with its location not on the record. Auditor changes are not on the record, as this register has no lifecycle type map yet.",
   "title": "Auditor"
  },
  {
   "id": "events",
   "text": "Listing, delisting, name change, domicile change and segment move are not on the record, as this register has no lifecycle type map yet. The halt flag is listed, not halted.",
   "title": "Events and halts"
  },
  {
   "id": "orderability",
   "text": "For the elective professional client category the outcome is signal ACM-200 and is determinable. For the eligible counterparty category the outcome is signal ACM-200 and is determinable. The rule version is acm-68000/uk/product-governance-fca-prod-sourcebook/r1, and the chapter is as of 2026-11-04.",
   "title": "Orderability"
  },
  {
   "id": "coverage",
   "text": "No research houses were found on the issuer's own investor-relations page as read.",
   "title": "Coverage"
  },
  {
   "id": "open_research",
   "text": "One openly published research note is on the record, by Hardman & Co Life Sciences Research, dated 2021-05-14.",
   "title": "Open research"
  },
  {
   "id": "licensed",
   "text": "Licensed research: none loaded. A licensed row is served only to an agent whose firm holds that licence (licensor, entitlement). No licensed row is loaded.",
   "title": "Licensed"
  },
  {
   "id": "depth",
   "text": "No issuer years are sealed. The market's vintage is not sealed, and no earliest sealed date is recorded. The live record began 2026-09-11. The years 2021, 2022, 2023, 2024, 2025 and 2026 are sealed in the store but not served as of a date, and the as-of door answers not_sealed.",
   "title": "As-of depth"
  },
  {
   "id": "sources",
   "text": "11 source pages are named on this page; every value above carries its own source page and read date in the numbers.",
   "title": "Sources"
  }
 ],
 "sources": [
  {
   "for": "identity.exchange",
   "source": "https://www.londonstockexchange.com/live-markets/market-data-dashboard/price-explorer"
  },
  {
   "for": "identity.isin",
   "source": "https://api.londonstockexchange.com/api/gw/lse/instruments/alldata/CIZ"
  },
  {
   "for": "identity.jurisdiction",
   "source": "https://find-and-update.company-information.service.gov.uk/company/06133765"
  },
  {
   "for": "identity.lei",
   "source": "https://mapping.gleif.org/api/v2/isin-lei/latest/download"
  },
  {
   "for": "identity.sector",
   "source": "https://www.londonstockexchange.com/stock/CIZ/cizzle-biotechnology-holdings-plc/company-page"
  },
  {
   "for": "the disclosure lines",
   "source": "https://mcp.uk-cm-kg.ai/events/LSE/CIZ"
  },
  {
   "for": "the halt flag",
   "source": "https://marketsecurities.fca.org.uk/officiallist"
  },
  {
   "for": "the auditor",
   "source": "https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotechnology-Holdings-PLC-Final-Annual-report-and-financial-statements-31-December-2023-Final-unsigned-29-April-2024.pdf"
  },
  {
   "for": "the orderability chapter",
   "source": "https://mcp.uk-cm-kg.ai/book/aio.json"
  },
  {
   "for": "open research",
   "source": "https://cizzlebiotechnology.com/wp-content/uploads/2025/03/Cizzle-Biotech-Initiation-report-%E2%80%93-14-May-2021.pdf"
  },
  {
   "for": "the record",
   "source": "https://mcp.uk-cm-kg.ai/record/LSE/CIZ"
  }
 ],
 "title": "CIZZLE BIOTECHNOLOGY HOLDINGS PLC (CIZ) — research page",
 "writer": {
  "by": "Claude through the platform account, Haiku class; one pass; checked against the numbers",
  "engine": "claude-haiku-5-5"
 }
}